학력
연구 업적
주요학술논문
Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription, NATURE COMMUNICATIONS, 13권,2089호, 2022
Emerging roles of PHLPP phosphatases in metabolism, BMB REPORTS, 54권,9호, pp. 451~457, 2021
Effects of human collagen alpha-1 type I-derived proteins on collagen synthesis and elastin production in human dermal fibroblasts, BMB REPORTS, 54권,6호, pp. 329~334, 2021
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis, SCIENCE TRANSLATIONAL MEDICINE, 13권,599호, 2021
Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver, NATURE COMMUNICATIONS, 12권,1호, 2021
A new aspect of an old friend: the beneficial effect of metformin on anti-tumor immunity, BMB REPORTS, 53권,10호, pp. 512~520, 2020
Human collagen alpha-2 type I stimulates collagen synthesis, wound healing, and elastin production in normal human dermal fibroblasts (HDFs), BMB REPORTS, 53권,10호, pp. 539~544, 2020
Liver-selective gamma-secretase inhibition ameliorates diet-induced hepatic steatosis, dyslipidemia and atherosclerosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 527권,4호, pp. 979~984, 2020
Targeting of Secretory Proteins as a Therapeutic Strategy for Treatment of Nonalcoholic Steatohepatitis (NASH), INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21권,7호, 2020
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis, SCIENCE TRANSLATIONAL MEDICINE, 10권,468호, 2018
Endothelial cell CD36 optimizes tissue fatty acid uptake, JOURNAL OF CLINICAL INVESTIGATION, 128권,10호, pp. 4329~4342, 2018
gamma-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor, CELL METABOLISM, 27권,4호, pp. 816~816, 2018
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis, GASTROENTEROLOGY, 153권,6호, pp. 1568~1568, 2017
"Free" Raptor - a novel regulator of metabolism, CELL CYCLE, 15권,9호, pp. 1174~1175, 2016
Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity, MOLECULAR METABOLISM , 2016
mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2, NATURE COMMUNICATIONS, 7권, 2016
특허